| Identification | Back Directory | [Name]
4-BROMO-2-CHLOROANISOLE | [CAS]
50638-47-6 | [Synonyms]
Chloro-4-bromoanisole
4-BROMO-2-CHLOROANISOLE
2-Chloro-4-bromoanisole
3-Chloro-4-methoxyphenyl bromide
1-Bromo-3-chloro-4-methoxybenzene
2-chloro-4-Bromo-1-methoxy-benzene
Benzene,4-bromo-2-chloro-1-methoxy-
Methyl(2-chloro-4-bromophenyl) ether | [EINECS(EC#)]
256-672-2 | [Molecular Formula]
C7H6BrClO | [MDL Number]
MFCD00128076 | [MOL File]
50638-47-6.mol | [Molecular Weight]
221.48 |
| Chemical Properties | Back Directory | [Melting point ]
68.5-70.5°C | [Boiling point ]
242℃ | [density ]
1.564 | [Fp ]
100℃ | [storage temp. ]
Sealed in dry,Room Temperature | [Appearance]
Off-white to pale purple Solid |
| Hazard Information | Back Directory | [Uses]
4-Bromo-2-chloro-1-methoxybenzene is used in the preparation of allosteric inhibitors hepatitis C polymerase in the form of dihydropyrones. Also used in the discovery of 5-HT6 reveptor ligands affecting serotonin levels and potential application to neuropsychopharmacology. | [References]
[1] Patent: US2009/209529, 2009, A1. Location in patent: Page/Page column 24
[2] Patent: US4623650, 1986, A
[3] Angewandte Chemie - International Edition, 2014, vol. 53, # 25, p. 6443 - 6448
[4] Angew. Chem., 2014, vol. 126, # 25, p. 6561 - 6566
[5] Angewandte Chemie - International Edition, 2013, vol. 52, # 35, p. 9144 - 9148 |
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