50908-62-8

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50908-62-8 Structure

Identification	Back Directory
[Name] 5'-(N-CYCLOPROPYL)CARBOXAMIDOADENOSINE
[CAS] 50908-62-8
[Synonyms] CPCA NCPCA n-cyclopropyladenosine-5’-carboxamide 5'-N-Cyclopropylcarboxamide adenosine 5'-(N-CYCLOPROPYL)CARBOXAMIDOADENOSINE adenosine-5’-(n-cyclopropyl)carboxamide 5'-(N-CYCLOPROPYL)-CARBOXAMIDOADENOSINE POTENT A2 ADENOSINE R 1-(6-amino-9h-purin-9-yl)-n-cyclopropyl-1-deoxy-ribofuranuronamid 1-(6-amino-9h-purin-9-yl)-n-cyclopropyl-1-deoxyribofuranuronamide 1-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-β-D-ribofuranuronamide N-Cyclopropyl-1-(6-amino-9H-purine-9-yl)-1-deoxy-β-D-ribofuranuronamide β-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy- 5'(NCyclopropyl)carboxamidoadenosine,5' (N Cyclopropyl)carboxamidoadenosine (2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-N-cyclopropyl-3,4-dihydroxytetrahydrofuran-2-carboxamide
[Molecular Formula] C13H16N6O4
[MDL Number] MFCD00055130
[MOL File] 50908-62-8.mol
[Molecular Weight] 320.3

Chemical Properties	Back Directory
[Boiling point ] 459.21°C (rough estimate)
[density ] 1.2633 (rough estimate)
[refractive index ] 1.7000 (estimate)
[storage temp. ] 2-8°C
[solubility ] DMF: 25 mg/ml; DMSO: 14 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ] A crystalline solid
[pka] 12.88±0.70(Predicted)

Hazard Information	Back Directory
[Description] 5''-(N-Cyclopropyl)carboxamidoadenosine is a specific adenosine A₂ receptor agonist with antipyretic and anticonvulsant activity. It stimulates the production of cyclic AMP in CHO-K1 cells with an EC₅₀ value of 5.3 μM.
[Uses] 5'-(N-Cyclopropyl)carboxamidoadenosine (CPCA) is an adenosine A2 receptor agonist[1].
[storage] Store at -20°C
[References] [1] J Malhotra, et al. Effect of adenosine receptor modulation on pentylenetetrazole-induced seizures in rats. Br J Pharmacol. 1997 Jan;120(2):282-8. DOI:10.1038/sj.bjp.0700869

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