| Identification | Back Directory | [Name]
H-ABU-OME HCL | [CAS]
56545-22-3 | [Synonyms]
L-2-Abu-OMe HCl
H-ABU-OME HCL USP/EP/BP
Methyl L-homoalaninate HCl
Methyl (S)-2-aMinobutanoate HCl
L-2-AMINOBUTYRIC ACID METHYL ESTER HCL
Methyl L-2-aminobutanoate hydrochloride
Methyl (S)-2-aminobutyrate hydrochloride
Methyl (S)-2-aminobutanoate hydrochloride
(S)-2-Aminobutanoic Acid Methyl Ester HCl
(S)-methyl 2-aminobutanoate hydrochloride
Methyl (2S)-2-aminobutanoate hydrochloride
L-α-AMinobutyric Acid Methyl Ester Hydrochloride
L-2-AMinobutyric Acid Methyl Ester Hydrochloride
L-2-Amino butanoic acid methyl ester hydrochloride
(S)-2-AMinobutanoic Acid Methyl Ester Hydrochloride
(S)-2-AMino-butanoic Acid Methyl Ester Hydrochloride | [Molecular Formula]
C5H12ClNO2 | [MDL Number]
MFCD09037399 | [MOL File]
56545-22-3.mol | [Molecular Weight]
153.607 |
| Chemical Properties | Back Directory | [Melting point ]
116-117℃ | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Aqueous Acid (Sparingly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Intermediate in the preparation of Ergonovine (E597800) derivatives. | [Synthesis]
The general procedure for the synthesis of DL-2-aminobutyric acid methyl ester hydrochloride from methanol and Boc-L-2-aminobutyric acid was as follows: 10.0 g (49.2 mmol) of Boc-L-2-aminobutyric acid was dissolved in 100 mL of methanol, and 6 mL (82.2 mmol) of thionyl chloride was added slowly and dropwise at 0 °C. The reaction mixture was stirred at room temperature for 14 h before the solvent was removed by vacuum evaporation. A product of 7.6 g (101% yield) was obtained. The structure of the product was confirmed by electrospray mass spectrometry (ES-MS) and the molecular ion peak (M + H)+ was observed as 118. | [References]
[1] Patent: US2010/144681, 2010, A1. Location in patent: Page/Page column 67 |
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