| Identification | Back Directory | [Name]
GSK-3β Inhibitor XI | [CAS]
626604-39-5 | [Synonyms]
GSK3β Inhibitor XI
GSK 3B Inhibitor XI
GSK-3β Inhibitor XI
4-[1-(3-Hydroxypropyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-(pyrazin-2-yl)pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 3-[1-(3-hydroxypropyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-(2-pyrazinyl)- | [Molecular Formula]
C18H15N5O3 | [MDL Number]
MFCD09037534 | [MOL File]
626604-39-5.mol | [Molecular Weight]
349.34 |
| Hazard Information | Back Directory | [Description]
ZUN04395, also known as GSK3β inhibitor XI, is a potent inhibitor of glycogen synthase kinase 3β. | [Uses]
GSK-3b Inhibitor XI (Compound 33) is a potent and selective GSK3β inhibitor, with a Ki value of 25 nM. GSK-3b Inhibitor XI increases glycogen synthase (GS) activity. GSK-3b Inhibitor XI can be used for research on type 2 diabetes and Alzheimer’s disease[1]. | [IC 50]
GSK-3β | [References]
[1] O'Neill, et al. Design, synthesis, and biological evaluation of novel 7-azaindolylheteroaryl-maleimides as potent and selective glycogen synthase kinase-3β (GSK-3β) inhibitors. Bioorg. Med. Chem. 12(12), 3167-3185 (2004). |
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| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|