| Identification | Back Directory | [Name]
(20S)-3β,20-Bis(dimethylamino)pregna-5-ene | [CAS]
6869-45-0 | [Synonyms]
Kurchessine
Irehdiamine I
(20S)-3β,20-Bis(dimethylamino)pregna-5-ene
(20S)-N,N,N',N'-Tetramethylpregn-5-ene-3β,20-diamine | [Molecular Formula]
C25H44N2 | [MOL File]
6869-45-0.mol | [Molecular Weight]
372.63 |
| Hazard Information | Back Directory | [Description]
A pregnene alkaloid found in the bark of Holarrhena antidysenterica Wall. and
also present in the leaves of Sarcococca pruni!ormis Lindl., the base forms colour_x0002_less crystals from Me2CO and has [α]20D - 37° (c 1.90, CHCl3), - 17° (c 1.OS,
MeOH). It contains three methyl groups and two dimethylamino groups in the
molecule. The alkaloid is characterized as the crystalline perchlorate, m.p. 277-
9°C (dec.) or the picrate, m.p. 228-230°C. The structure has been established as
3 ,20 -bis (dimethylamino)pregn-S-ene. It is identical with saracodinine. | [Uses]
Kurchessine (Sarcodinine) is an alkaloid that can be isolated from the stem bark of Holarrhena antidysenterica[1]. | [Definition]
ChEBI:Kurchessine is an aza-steroid. | [References]
Tschesche, Wiensz., Chem. Ber., 91, lS04 (19S8)
Tschesche, Otto., ibid, 95, 1144 (1962)
Chatterjee et aI., Tetrahedron Lett., 67 (1965)
Structure:
Labler, Sorm., Collect. Czech. Chem. Commun., 28,2345 (1963) |
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