| Identification | Back Directory | [Name]
ROHITUKINE | [CAS]
71294-60-5 | [Synonyms]
NSC623611
NSC-623611
NSC 623611
ROHITUKINE
5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-2-methylchromen-4-one
5,7-Dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-2-methyl-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-2-methyl- | [Molecular Formula]
C16H19NO5 | [MDL Number]
MFCD00878456 | [MOL File]
71294-60-5.mol | [Molecular Weight]
305.33 |
| Hazard Information | Back Directory | [Uses]
Rohitukine is an alkaloid with analgesic and anti-inflammatory activities[1]. | [Definition]
ChEBI: Rohitukine is a member of the class of chromones that is 4H-chromen-4-one in which the hydrogens at positions 2,5,7 and 8 are replaced by methyl, hydroxy, hydroxy, and (3S,4R)-3-hydroxy-1-methylpiperidin-4-yl groups, respectively. It is an alkaloid initially isolated from Amoora rohituka and is a precursor of the anti-cancer compound flavopiridol. It has a role as a plant metabolite, an antineoplastic agent, an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor, a fungal metabolite, an anti-inflammatory agent, an anti-ulcer drug, an anticholesteremic drug and an antileishmanial agent. It is a hydroxypiperidine, a tertiary amino compound, a member of chromones, a member of resorcinols and an alkaloid. | [References]
[1] Houghton P J, et al. Further chromone alkaloids from Schumanniophyton magnificum[J]. Planta Medica, 1987, 53(03): 262-264. DOI:10.1055/s-2006-962698 |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
|