| Identification | Back Directory | [Name]
11-DEHYDROCORTICOSTERONE | [CAS]
72-23-1 | [Synonyms]
NSC-9702
11-Oxocorticosterone
KENDALL'S COMPOUND A
KENDALL'S COMPOUND ''A''
11-DEHYDROCORTICOSTERONE
4-PREGNEN-21-OL-3,11,20-TRIONE
4-Pregene-21-ol-3,11,20-trione
11-dehydrocorticosterone crystalline
21-hydroxypregn-4-ene-3,11,20-trione
21-HYDROXY-4-PREGNENE-3,11,20-TRIONE
Pregn-4-ene-3,11,20-trione, 21-hydroxy-
Corticosterone Impurity 2 (11-Dehydro Corticosterone)
11-Dehydrocorticosterone-[3,4,20,21-13C4] in Methanol
17-glycoloyl-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-quinone
17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
17-(2-hydroxyethanoyl)-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione | [EINECS(EC#)]
200-776-2 | [Molecular Formula]
C21H28O4 | [MDL Number]
MFCD00046217 | [MOL File]
72-23-1.mol | [Molecular Weight]
344.44 |
| Chemical Properties | Back Directory | [Melting point ]
183.5°C | [Boiling point ]
399.53°C (rough estimate) | [density ]
1.0556 (rough estimate) | [refractive index ]
1.4430 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Dioxane (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.95±0.10(Predicted) | [color ]
White to Pale Yellow | [optical activity]
+34725 (c 0.23, C6H6) |
| Hazard Information | Back Directory | [Uses]
11-Dehydrocorticosterone is a precursor to corticosterone (C695700), converted by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) which plays a role in glucocorticoid-induced insulin resistance. | [Definition]
ChEBI: An 11-oxo steroid that is corticosterone in which the hydroxy substituent at the 11beta position has been oxidised to give the corresponding ketone. | [IC 50]
Human Endogenous Metabolite |
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