Identification | Back Directory | [Name]
GIP (1-39) | [CAS]
725474-97-5 | [Synonyms]
GIP (1-39) M.W. 4633.21 C210H316N56O61S Gastric Inhibitory Polypeptide (1-39) (human) | [Molecular Formula]
C210H316N56O61S | [MDL Number]
MFCD07785216 |
Chemical Properties | Back Directory | [storage temp. ]
Desiccate at -20°C | [form ]
Powder | [Water Solubility ]
Soluble to 10 mg/ml in water | [Sequence]
Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-Arg-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Ser-Asp-Trp-Lys-His-Asn |
Hazard Information | Back Directory | [Description]
Endogenous truncated form of the incretin hormone GIP. More potent at stimulating glucose-dependent insulin secretion from rat pancreaticβ-cells than GIP. | [Uses]
GIP (1-39) (Gastric inhibitory peptide (1-39) (porcine)) is an insulinotropic peptide that stimulats insulin secretion from rat pancreatic islets. GIP (1-39) at 100 nM was able to significantly increase intracellular Ca2+ concentration ([Ca2+]i), and capable of enhancing exocytosis[1]. | [storage]
Desiccate at -20°C | [References]
[1] Xie L, et al. GIP1-39, a novel insulinotropic peptide form and aspects on its mechanism of action. Regul Pept. 2004 Sep 15;121(1-3):107-12. DOI:10.1016/j.regpep.2004.04.013 |
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