| Identification | Back Directory | [Name]
cyclo (Arg-Ala-Asp-d-Phe-Lys) | [CAS]
756500-23-9 | [Synonyms]
c(RADfK)
CYCLO(RADFK), BR
Cyclo(RADfK),c(RADfK), BR
cyclo (Arg-Ala-Asp-d-Phe-Lys)
Cyclo(-Arg-Ala-Asp-D-Phe-Lys) trifluoroacetate salt
Cyclo(L-alanyl-L-α-aspartyl-D-phenylalanyl-L-lysyl-L-arginyl)
Cyclo(L-alanyl-L-α-aspartyl-D-phenylalanyl-L-lysyl-L-arginyl)
2-((2S,5R,8S,11S,14S)-8-(4-aminobutyl)-5-benzyl-11-(3-guanidinopropyl)-14-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)aceticacid | [Molecular Formula]
C28H43N9O7 | [MDL Number]
MFCD28016481 | [MOL File]
756500-23-9.mol | [Molecular Weight]
617.71 |
| Chemical Properties | Back Directory | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
4.01±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Water : ≥ 25 mg/mL (40.47 mM) | [Sequence]
Cyclo(Arg-Ala-Asp-d-Phe-Lys) | [InChIKey]
SMFHXHGBDFBWOX-OVACWLFONA-N | [SMILES]
C(C1C=CC=CC=1)[C@H]1NC([C@@]([H])(NC([C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC1=O)C)=O)CC(=O)O)=O |&1:7,10,14,18,29,r| |
| Hazard Information | Back Directory | [Uses]
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis. | [References]
[1] Srivatsan A, et al. Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics withenhanced tumor-imaging and photosensitizing (PDT) efficacy. Mol Pharm. 2011 Aug 1;8(4):1186-1197. DOI:10.1021/mp200018y |
|
| Company Name: |
Alabiotech Inc.
|
| Tel: |
001-619-354-5251 |
| Website: |
www.alabiotech-e.com |
|