| Identification | Back Directory | [Name]
N-(4'-Cyano-[1,1'-biphenyl]-3-yl-N-(3-pyridinylmethyl)-ethanesulfonamidehydrochloride | [CAS]
856702-40-4 | [Synonyms]
CBiPES
CBiPES HCl
CBiPES hydrochloride
N-(4'-cyanobiphenyl-3-yl)-N-(pyridin-3-ylMethyl)ethanesulfonaMide hydrochloride
N-(4'-Cyano-[1,1'-biphenyl]-3-yl-N-(3-pyridinylmethyl)-ethanesulfonamidehydrochloride | [Molecular Formula]
C21H20ClN3O2S | [MDL Number]
MFCD18086913 | [MOL File]
856702-40-4.mol | [Molecular Weight]
413.92 |
| Hazard Information | Back Directory | [Uses]
CBiPES Hydrochloride is a selective positive allosteric modulator of the mGluR-2. | [Biological Activity]
CBiPES is a positive allosteric modulator of the mGlu2 receptor. CBiPES attenuates stress-induced hyperthermia and blocks the hyperlocomotor effects of PCP in murine models. In r at brainCBiPES attenuates ketamine-induced increase in extracellular histamine concentration. This compound is a sulfonamidedifferent chemical class from other mGlu2R agonists in the Sigma catalog. |
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