| Identification | Back Directory | [Name]
FUBP1–IN-1 | [CAS]
883003-62-1 | [Synonyms]
FUBP1–IN-1
Pyrazolo[1,5-a]pyrimidine, 5-(3,4-dimethoxyphenyl)-2-(2-thienyl)-7-(trifluoromethyl)- | [Molecular Formula]
C19H14F3N3O2S | [MOL File]
883003-62-1.mol | [Molecular Weight]
405.39 |
| Chemical Properties | Back Directory | [density ]
1.42±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 16.67 mg/mL (41.12 mM) | [form ]
Solid | [pka]
-2.01±0.30(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
FUBP1-IN-1 is a potent FUSE binding protein 1 (FUBP1) inhibitor which interferes with the binding of FUBP1 to its single stranded target DNA FUSE sequence , with an IC50 value of 11.0 μM[1]. | [storage]
Store at -20°C | [References]
[1] Hauck S, et al. Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors. Bioorg Med Chem. 2016 Nov 15;24(22):5717-5729. DOI:10.1016/j.bmc.2016.09.015 |
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MedChemExpress
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021-58955995 |
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www.medchemexpress.com |
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