| Identification | Back Directory | [Name]
3-(2-hydroxyethoxy)propanoic acid | [CAS]
89211-34-7 | [Synonyms]
89211-34-7
OH-PEG1-COOH
Hydroxy-PEG1-acid
3-(2-hydroxyethoxy)propanoic acid
Propanoic acid, 3-(2-hydroxyethoxy)- | [Molecular Formula]
C5H10O4 | [MDL Number]
MFCD11618155 | [MOL File]
89211-34-7.mol | [Molecular Weight]
134.13 |
| Chemical Properties | Back Directory | [Boiling point ]
127-130 °C(Press: 2 Torr) | [density ]
1.224±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
4.26±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Non-cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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