| Identification | Back Directory | [Name]
TRPC6-IN-1 | [CAS]
901715-05-7 | [Synonyms]
TRPC6-IN-1
1-Piperidinecarboxylic acid, 4-[3-(4-fluorophenyl)-7-hydroxy-2-methylpyrazolo[1,5-a]pyrimidin-5-yl]-, ethyl ester | [Molecular Formula]
C21H23FN4O3 | [MDL Number]
MFCD14755966 | [MOL File]
901715-05-7.mol | [Molecular Weight]
398.43 |
| Chemical Properties | Back Directory | [density ]
1.37±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
5.46±0.53(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
TRPC6-IN-1 is a Transient Receptor Potential Canonical 6 Channel (TRPC6) inhibitor, with an EC50 of 4.66 μM. | [Definition]
ChEBI: 4-[3-(4-fluorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperidinecarboxylic acid ethyl ester is a ring assembly and a member of pyrazoles. | [storage]
Store at -20°C | [References]
[1] Qu C, et al. Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. J Med Chem. 2017 Jun 8;60(11):4680-4692. DOI:10.1021/acs.jmedchem.7b00304 |
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MedChemExpress
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021-58955995 |
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www.medchemexpress.com |
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