| Identification | Back Directory | [Name]
Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- | [CAS]
928712-10-1 | [Synonyms]
HG106
Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]- | [Molecular Formula]
C15H13ClN4O2 | [MOL File]
928712-10-1.mol | [Molecular Weight]
316.74 |
| Chemical Properties | Back Directory | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 21 mg/mL (66.30 mM);Ethanol: Insoluble | [form ]
Solid | [pka]
10.89±0.43(Predicted) | [color ]
Off-white to light yellow | [Water Solubility ]
Water: Insoluble |
| Hazard Information | Back Directory | [Biological Activity]
HG106, a potent SLC7A11 inhibitor, leads to enhanced ROS generation, ER stress, and ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD). | [References]
[1] Hu K, et al. J Clin Invest. 2020 Apr 1;130(4):1752-1766. |
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DC Chemicals
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