| Identification | Back Directory | [Name]
2-(5,5-Dimethyl-2-oxo-2λ5-[1,3,2]dioxaphosphinan-2-yl)-2-methyl-3,4-dihydro-2H-pyrrole 1-oxide, 5-(2,2-Dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide | [CAS]
934182-09-9 | [Synonyms]
CYPMPO
OSKIWEPJAIOTFB-UHFFFAOYSA-N
5-(2,2-Dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide
2-(5,5-Dimethyl-2-oxo-2λ5-[1,3,2]dioxaphosphinan-2-yl)-2-methyl-3,4-dihydro-2H-pyrrole 1-oxide
2H-Pyrrole, 2-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-3,4-dihydro-2-methyl-, 1-oxide
2-(5,5-Dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-1-hydroxy-2-methyl-3,4-dihydro-2H-1λ5-pyrrol-1-yl
2-(5,5-Dimethyl-2-oxo-2λ5-[1,3,2]dioxaphosphinan-2-yl)-2-methyl-3,4-dihydro-2H-pyrrole 1-oxide, 5-(2,2-Dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide | [Molecular Formula]
C10H18NO4P | [MDL Number]
MFCD11045266 | [MOL File]
934182-09-9.mol | [Molecular Weight]
247.23 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
Soluble in DMSO (up to 20 mg/ml), in DMF (up to 25 mg/ml) or in PBS-pH 7.2 (up to 10 mg/ml). | [form ]
Solid | [color ]
Off-white to light yellow | [Stability:]
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months. Aqueous solutions are not stable and must be used within one working day. |
| Hazard Information | Back Directory | [Description]
CYPMPO (934182-09-9) is a free radical spin-trap with hydroxyl and superoxide free radical trapping capabilities similar to DEPMPO (Cat.# 10-4502). Better solubility and increased half-life in aqueous buffers can give CYPMPO a practical advantage over DEPMPO in some experiments. | [Uses]
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor?activity[1]. | [storage]
Store at -20°C | [References]
1) Kamibayashi?et al. (2006)?Synthesis and characterization of a practically better DEPMPO-type spin trap, 5-(2,2-dimethyl-1,3-propoxycyclophosphoryl)-5-methyl-1-pyrroline N-oxide (CYPMPO); Free Radic. Res.?40?1166 |
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