| Identification | Back Directory | [Name]
6-O-Methacryloyltrilobolide | [CAS]
950685-51-5 | [Synonyms]
6-O-Methacrylate
6-O-Methacryloyltrilobolide
2-Propenoic acid, 2-methyl-, (3aR,4R,4aS,5R,8R,8aR,9S,9aR)-8,9-bis(acetyloxy)dodecahydro-5-hydroxy-5,8a-dimethyl-3-methylene-2-oxonaphtho[2,3-b]furan-4-yl ester | [Molecular Formula]
C23H30O9 | [MDL Number]
MFCD34471092 | [MOL File]
950685-51-5.mol | [Molecular Weight]
450.48 |
| Hazard Information | Back Directory | [Uses]
6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity[1][2]. | [IC 50]
Plasmodium | [References]
[1] That QT, et, al. Wedelolides A and B: novel sesquiterpene delta-lactones, (9R)-eudesman-9,12-olides, from Wedelia trilobata. J Org Chem. 2007 Sep 14;72(19):7102-5. DOI:10.1021/jo070771m
[2] Li Y, et, al. Eudesmanolides from Wedelia trilobata (L.) Hitchc. as potential inducers of plant systemic acquired resistance. J Agric Food Chem. 2013 Apr 24;61(16):3884-90. DOI:10.1021/jf400390e |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|