1050477-27-4
中文名稱
1050477-27-4
英文名稱
4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
CAS
1050477-27-4
分子式
C21H22N4O3
分子量
378.42
MOL 文件
1050477-27-4.mol
更新日期
2025/05/20 10:43:19
1050477-27-4 結(jié)構(gòu)式
基本信息
中文別名
(RAC)-FINERENONE 英文別名
(Rac)-Finerenone(Rac)-BAY 94-8862
4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-1,6-naphthyridine-3-carboxamide
1,6-Naphthyridine-3-carboxamide, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-
所屬類別
醫(yī)藥中間體：原料藥中間體物理化學(xué)性質(zhì)
沸點(diǎn)554.7±50.0 °C(Predicted)
密度1.29±0.1 g/cm3(Predicted)
蒸氣壓0Pa at 25℃
溶解度DMSO : 62.5 mg/mL (165.16 mM; Need ultrasonic)
酸度系數(shù)(pKa)14.76±0.40(Predicted)
形態(tài)Solid
顏色White to off-white
水溶解性18.3mg/L at 20℃
InChIInChI=1S/C21H22N4O3/c1-5-28-21-18-17(14-7-6-13(9-22)8-15(14)27-4)16(20(23)26)12(3)25-19(18)11(2)10-24-21/h6-8,10,17,25H,5H2,1-4H3,(H2,23,26)
InChIKeyBTBHLEZXCOBLCY-UHFFFAOYSA-N
SMILESN1C2=C(C(OCC)=NC=C2C)C(C2=CC=C(C#N)C=C2OC)C(C(N)=O)=C1C
LogP2.59 at 25℃
