1196800-39-1
中文名稱(chēng)
1196800-39-1
英文名稱(chēng)
Omadacycline (hydrochloride)
CAS
1196800-39-1
分子式
C29H41ClN4O7
分子量
593.12
MOL 文件
1196800-39-1.mol
更新日期
2024/11/15 18:20:32
1196800-39-1 結(jié)構(gòu)式
基本信息
英文別名
omadacycline HClPTK0796 hydrochloride
PTK-0796 hydrochloride
PTK 0796 hydrochloride
Amadacycline hydrochloride
Omadacycline (hydrochloride)
PTK 0796 HYDROCHLORIDE
PTK-0796 HYDROCHLORIDE
PTK0796 HYDROCHLORIDE
AMADACYCLINE HYDROCHLORIDE
(4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-9-[(2,2-dimethylpropylamino)methyl]-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
應(yīng)用領(lǐng)域
用途一
Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The primary effect of omadacycline is on bacterial protein synthesis, inhibiting protein synthesis with a potency greater than that of tetracycline. The binding site for omadacycline is similar to that for tetracycline.常見(jiàn)問(wèn)題列表
概述
Omadacycline (PTK 0796) hydrochloride，首創(chuàng)的具有口服活性的氨基甲基環(huán)素抗菌劑，是一種四環(huán)素類(lèi)抗生素。Omadacycline hydrochloride 通過(guò)與 30S 核糖體亞基結(jié)合來(lái)抑制細(xì)菌蛋白質(zhì)的合成。Omadacycline hydrochloride 對(duì)多種細(xì)菌表現(xiàn)出活性，包括好氧和厭氧革蘭氏陽(yáng)性細(xì)菌和革蘭氏陰性細(xì)菌，非典型病原體。Omadacycline hydrochloride 可用于研究急性細(xì)菌性皮膚和皮膚結(jié)構(gòu)感染，感染性肺炎和尿路感染。1196800-39-1價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | HY-14865C | 1196800-39-1 Omadacycline hydrochloride | 1196800-39-1 | 2mg | 550元 |
| 2025/05/22 | HY-14865C | 1196800-39-1 Omadacycline hydrochloride | 1196800-39-1 | 5mg | 1000元 |
| 2025/05/22 | HY-14865C | 1196800-39-1 Omadacycline hydrochloride | 1196800-39-1 | 10mM * 1mLin DMSO | 1305元 |