193273-69-7
中文名稱
卡普瑞林酒石酸鹽
英文名稱
CaproMorelin Tartrate
CAS
193273-69-7
分子式
C32H41N5O10
分子量
655.695
MOL 文件
193273-69-7.mol
更新日期
2025/08/15 13:22:27
193273-69-7 結(jié)構(gòu)式
基本信息
中文別名
酒石酸卡莫瑞林卡普瑞林酒石酸鹽
卡普瑞林L-酒石酸鹽
英文別名
CS-2136CP 424391-18
CP-424391 tartrate
CaproMorelin Tartrate
CP 424391-18
CP-424391 TARTRATE
N-{2-[(3aS)-3a-benzyl-2-methyl-3-methylidene-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-1-(benzyloxy)-2-oxoethyl}-2-methylalaninamide 2,3-dihydroxybutanedioate (1:1)
所屬類別
有機(jī)原料：羧酸類化合物及衍生物物理化學(xué)性質(zhì)
熔點(diǎn)>150oC (dec.)
儲(chǔ)存條件Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度可溶于DMSO（少許）、甲醇（少許）
形態(tài)固體
顏色白色至淺黃色
水溶解性H2O: 20mg/mL, clear
穩(wěn)定性吸濕性
InChIKeyMJGRJCMGMFLOET-GTNBBHPYNA-N
SMILES[C@H](O)(C(=O)O)[C@@H](O)C(=O)O.C(C1C=CC=CC=1)[C@]12C(N(C)N=C1CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC1C=CC=CC=1)C2)=O |&1:0,5,17,28,r|
卡普瑞林酒石酸鹽價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | HY-15243 | 卡普瑞林酒石酸鹽 Capromorelin Tartrate | 193273-69-7 | 2mg | 500元 |
| 2025/05/22 | HY-15243 | 卡普瑞林酒石酸鹽 Capromorelin Tartrate | 193273-69-7 | 5mg | 700元 |
| 2025/05/22 | HY-15243 | 卡普瑞林酒石酸鹽 Capromorelin Tartrate | 193273-69-7 | 10mM * 1mLin DMSO | 1010元 |
常見(jiàn)問(wèn)題列表
生物活性
Capromorelin Tartrate 是一種可口服的，有效的growth hormone secretagogue receptor (GHSR)激動(dòng)劑，對(duì)hGHS-R1a的Ki值為 7 nM。靶點(diǎn)
Ki: 7 nM (hGHS-R1a)
體外研究
Capromorelin stimulates GH release in rat pituitary cell cultures with EC 50 of 3 nM.
體內(nèi)研究
Dogs receiving capromorelin (30 mg/mL) have food consumption that is significantly greater than dogs treated with placebo. All dogs in the capromorelin group gain weight by 0.52 kg, more than that of placebo group. Capromorelin shows enhanced intestinal absorption in rodent models and exhibits superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%]. Capromorelin stimulates GH release in anesthesized rat model, with ED 50 of 0.05 mg/kg iv.