848301-94-0
中文名稱
G3-C12
英文名稱
G3-C12
CAS
848301-94-0
分子式
C74H115N23O23S2
分子量
1758.99
MOL 文件
848301-94-0.mol
更新日期
2025/05/26 09:24:34
848301-94-0 結(jié)構(gòu)式
基本信息
英文別名
G3-C12L-Arginine, L-alanyl-L-asparaginyl-L-threonyl-L-prolyl-L-cysteinylglycyl-L-prolyl-L-tyrosyl-L-threonyl-L-histidyl-L-α-aspartyl-L-cysteinyl-L-prolyl-L-valyl-L-lysyl-
物理化學(xué)性質(zhì)
密度1.58±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)3.31±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
G3-C12價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | HY-P1592 | G3-C12 | 848301-94-0 | 1 mg | 900元 |
| 2025/05/22 | HY-P1592 | G3-C12 | 848301-94-0 | 5 mg | 2200元 |
| 2025/05/22 | HY-P1592 | G3-C12 | 848301-94-0 | 10 mg | 3300元 |
常見(jiàn)問(wèn)題列表
生物活性
G3-C12 是 galectin-3 結(jié)合肽，Kd 值為 88 nM，具有抗腫瘤活性。靶點(diǎn)
Kd: 88 nM (Galectin-3)
體外研究
G3-C12 is a galectin-3 binding peptide, with high affinity (K d ) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.