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85320-68-9

基本信息

英文別名
Amosulalol
Amosulalol USP/EP/BP
Benzenesulfonamide, 5-[1-hydroxy-2-[[2-(2-methoxyphenoxy)ethyl]amino]ethyl]-2-methyl-
Benzenesulfonamide, 5-[1-hydroxy-2-[[2-(2-methoxyphenoxy)ethyl]amino]ethyl]-2-methyl-, (+-)-
所屬類別
原料藥:β-腎上腺素受體阻斷藥

物理化學(xué)性質(zhì)

形態(tài)Solid
顏色White to off-white

應(yīng)用領(lǐng)域

用途一
Amosulalol is a potent antihypertensive with combined alpha and beta blocking properties. Indicated for the treatment of essential hypertension, it appears to possess a minimum of side-effects. Its beta-blocking property reduces the tachycardia associated with alpha-blockers, while its alpha-blocking activity reduces the peripheral vasoconstriction associated with beta-blockade.

常見問題列表

概述
氨磺洛爾 是一種口服有效的 α1/β1-腎上腺素能受體的雙抑制劑。Amosulalol 通過抑制 α1-腎上腺素能受體,表現(xiàn)出抗高血壓活性。Amosulalol 通過抑制 β1-腎上腺素能受體,降低自發(fā)性高血壓大鼠 (SHR) 的心率和血漿腎素活性 (PRA) 的反射性增加。
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