947687-01-6
中文名稱
7,11-二乙基-10-羥基喜樹堿
英文名稱
7,11-Diethyl-10-hydroxycaMptothecin
CAS
947687-01-6
分子式
C24H24N2O5
分子量
420.46
MOL 文件
947687-01-6.mol
更新日期
2024/09/16 13:07:48
947687-01-6 結(jié)構(gòu)式
基本信息
中文別名
伊立替康EP雜質(zhì)G伊立替康雜質(zhì)G(EP)
7,11-二乙基-10-羥基喜樹堿
伊立替康EP雜質(zhì)G(7,11-二乙基-10-羥基喜樹堿)
伊立替康EP雜質(zhì)G(7,11-二乙基!L-10-羥基喜樹堿)
(S)-4,8,11-三乙基-4,9-二羥基-1H-吡喃并[3',4':6,7]吲嗪并[1,2-B]喹啉-3,14-(4H,12H)-二酮
(S)-4,8,11-三乙基-4,9-二羥基-1H-吡喃并[3',4':6,7]吲哚并[1-2,B]喹啉-3,14(4H,12H) -二酮(伊立替康雜質(zhì))
英文別名
Irinotecan EP Impurity G(S)-4,8,11-triethyl-4,9-dihydroxy-
IRINOTECAN EP IMPURITY G (7,11-DIETHYL-10-HYDROXY CAMPTOTHECIN)
(S)-4,8,11-Triethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
(4S)-4,8,11-Triethyl-4,9-dihydroxy-1H-pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,8,11-triethyl-4,9-dihydroxy-, (4S)-
(S)-4,8,11-triethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione? (Irinotecan Impurity）
Irinotecan EP Impurity G/ Irinotecan Related Compound G (7,11-Diethyl-10-hydroxycamptothecin/ 8,11-Diethyl-9-Hydroxy Camptothecin)
所屬類別
醫(yī)藥中間體：原料藥中間體物理化學(xué)性質(zhì)
沸點(diǎn)798.1±60.0 °C(Predicted)
密度1.44±0.1 g/cm3(Predicted)
溶解度DMSO (Slightly, Heated)
酸度系數(shù)(pKa)9.43±0.40(Predicted)
形態(tài)Solid
顏色Light Yellow to Yellow
InChIInChI=1S/C24H24N2O5/c1-4-12-7-18-14(8-20(12)27)13(5-2)15-10-26-19(21(15)25-18)9-17-16(22(26)28)11-31-23(29)24(17,30)6-3/h7-9,27,30H,4-6,10-11H2,1-3H3/t24-/m0/s1
InChIKeyBQAJEBSARMNUPK-DEOSSOPVSA-N
SMILESN1C2C(=CC(O)=C(CC)C=2)C(CC)=C2CN3C(C=12)=CC1[C@](CC)(O)C(=O)OCC=1C3=O