N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
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- CAS號:
- 1042672-97-8
- 英文名:
- N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide
- 英文別名:
- CS-647;CS-2482;IRAK-IN-6;IRAK inhibitor 6;IRAK inhibitor 6 (IRAK-IN-6);IRAK inhibitor 6, 10 mM in DMSO;N-[2-methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-;N-(2-Methoxy-4-Morpholinophenyl)-2-(pyridin-3-yl)thiazole-4-carboxaMide;N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide;4-ThiazolecarboxaMide, N-[2-Methoxy-4-(4-Morpholinyl)phenyl]-2-(3-pyridinyl)-
- 中文名:
- N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
- 中文別名:
- IRAK 抑制劑 6;化合物IRAK INHIBITOR 6;化合物IRAK INHIBITOR 6,10 MM DMSO 溶液;N-(2-甲氧基-4-嗎啉苯基)-2-(吡啶-3-基)噻唑-4-甲酰胺;N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
- CBNumber:
- CB32604265
- 分子式:
- C20H20N4O3S
- 分子量:
- 396.46
- MOL File:
- 1042672-97-8.mol
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N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰化學(xué)性質(zhì)
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密度:
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1.335
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儲存條件:
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Sealed in dry,Store in freezer, under -20°C
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溶解度:
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insoluble in EtOH; insoluble in H2O; ≥9.9 mg/mL in DMSO
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形態(tài):
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solid
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酸度系數(shù)(pKa):
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10.19±0.70(Predicted)
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顏色:
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Light brown to brown
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N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰性質(zhì)、用途與生產(chǎn)工藝
IRAK inhibitor 6 是一種選擇性的Interleukin-1 receptor-associated kinase 4(IRAK4)抑制劑，IC50為 0.16 μM。
| Target | Value |
IRAK4
(Cell-free assay)
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0.16 μM
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IRAK inhibitor 6 significantly improves potency against IRAK-4. Potency effects additive, IRAK inhibitor 6 is the most active compound among these compound tested.
N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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| 2025/05/22 | HY-13280 | N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
IRAK inhibitor 6 | 1042672-97-8 | 1 mg | 600元 |
| 2025/05/22 | HY-13280 | N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
IRAK inhibitor 6 | 1042672-97-8 | 10mM * 1mLin DMSO | 1308元 |
N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
生產(chǎn)廠家
1042672-97-8, N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰 相關(guān)搜索:
- 抑制劑
- 藥靶配體
- 唑類
- 化合物IRAK INHIBITOR 6,10 MM DMSO 溶液
- N-(2-甲氧基-4-嗎啉苯基)-2-(吡啶-3-基)噻唑-4-甲酰胺
- 化合物IRAK INHIBITOR 6
- N-[2-甲氧基-4-(4-嗎啉基)苯基]-2-(3-吡啶基)-4-噻唑甲酰
- IRAK 抑制劑 6
- 1042672-97-8
- IRAK inhibitor 6 (IRAK-IN-6)
- IRAK inhibitor 6, 10 mM in DMSO
- Interleukin-1 receptor associated kinase,inhibit,Inhibitor,IL-1R associated kinase,IRAK inhibitor 6,IRAK inhibitor6,IRAK,IRAK inhibitor-6
- IRAK-IN-6
- CS-647
- CS-2482
- N-[2-methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-
- IRAK inhibitor 6
- N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide
- 4-ThiazolecarboxaMide, N-[2-Methoxy-4-(4-Morpholinyl)phenyl]-2-(3-pyridinyl)-
- N-(2-Methoxy-4-Morpholinophenyl)-2-(pyridin-3-yl)thiazole-4-carboxaMide