L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-
![L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]- Structure](CAS/20210305/GIF/133429-58-0.gif)
- CAS No.
- 133429-58-0
- Chemical Name:
- L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-
- Synonyms
- L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]-
- CBNumber:
- CB08582816
- Molecular Formula:
- C29H39N3O5
- Molecular Weight:
- 509.64
- MDL Number:
- MOL File:
- 133429-58-0.mol
| Boiling point | 732.8±60.0 °C(Predicted) |
|---|---|
| Density | 1.122±0.06 g/cm3(Predicted) |
| pka | 11.14±0.46(Predicted) |
| FDA UNII | UK3R4HLP9C |
L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]- Chemical Properties,Uses,Production
Uses
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) is a potent inhibitor of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (Ki = 460 nM). Z-LLF-CHO is also a NF-κB nuclear translocation inhibitor[1][2].
References
[1] Orlowski M, et al. Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. Biochemistry. 1993 Feb 16;32(6):1563-72. DOI:10.1021/bi00057a022
[2] Ding L, et al. Epstein-Barr virus encoded latent membrane protein 1 modulates nuclear translocation of telomerase reverse transcriptase protein by activating nuclear factor-kappaB p65 in human nasopharyngeal carcinoma cells. Int J Biochem Cell Biol. 2005 Sep;37(9):1881-9. DOI:10.1016/j.biocel.2005.04.012
L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-2-phenylethyl]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19904 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13173652190 | pomy@tanzhenbio.com | China | 1903 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 21356 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
