L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1)
![L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1) Structure](CAS/20211123/GIF/928821-41-4.gif)
- CAS No.
- 928821-41-4
- Chemical Name:
- L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1)
- Synonyms
- Seladelpar L-lysine salt;MBX-8025 lysine anhydrous;L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1)
- CBNumber:
- CB110663980
- Molecular Formula:
- C27H37F3N2O7S
- Molecular Weight:
- 590.66
- MDL Number:
- MOL File:
- 928821-41-4.mol
L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1) Properties
| form | Solid |
|---|---|
| color | White to off-white |
| FDA UNII | 75US2513Z8 |
L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1) Chemical Properties,Uses,Production
Uses
Seladelpar (MBX-8025) lysine is an orally active, potent and specific PPARδ agonist with an EC50 of 2 nM. Seladelpar lysine shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar lysine can be used for the study of primary biliary cholangitis[1].
References
[1] Bays HE, et al. MBX-8025, a novel peroxisome proliferator receptor-delta agonist: lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin. J Clin Endocrinol Metab. 2011 Sep;96(9):2889-97. DOI:10.1210/jc.2011-1061
[2] Haczeyni F, et al. The selective peroxisome proliferator-activated receptor-delta agonist seladelpar reverses nonalcoholic steatohepatitis pathology by abrogating lipotoxicity in diabetic obese mice. Hepatol Commun. 2017 Jul 31;1(7):663-674. DOI:10.1002/hep4.1072
L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1) Preparation Products And Raw materials
Raw materials
Preparation Products
L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19903 | 58 |
| Shanghai Mumin Biotechnology Co., Ltd | 17177768578 17177768578 | alisa@pemichem.com | China | 301 | 58 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 17702719238 | sales@sun-shinechem.com | China | 1040 | 64 |
| Xiamen Halosyntech Co., Ltd | 0592-6688068 18106901346 | qbl2015@halolife.cn | China | 116 | 55 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 20701 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Shanghai Mumin Biotechnology Co., Ltd | 58 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 64 |
| Xiamen Halosyntech Co., Ltd | 55 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from L-Lysine, compd. with 2-[4-[[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]thio]-2-methylphenoxy]acetic acid (1:1) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-29 | MBX-8025 lysine anhydrous
928821-41-4
|
US $2500.00-1520.00 / mg | 10g | TargetMol Chemicals Inc. |
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- MBX-8025 lysine anhydrous
928821-41-4
- US $2500.00-1520.00 / mg
- TargetMol Chemicals Inc.