Azido-PEG8-CH2CO2-PFP
- CAS No.
- 2182601-80-3
- Chemical Name:
- Azido-PEG8-CH2CO2-PFP
- Synonyms
- Azido-PEG8-CH2COO-PFP;Azido-PEG8-CH2CO2-PFP
- CBNumber:
- CB24849546
- Molecular Formula:
- C24H34F5N3O10
- Molecular Weight:
- 619.54
- MDL Number:
- MFCD31561139
- MOL File:
- 2182601-80-3.mol
Azido-PEG8-CH2CO2-PFP Chemical Properties,Uses,Production
Description
Azido-PEG8-CH2CO2-PFP is a monodisperse PEG molecule thathas an azide group and a PFP group. The azide group enable Click Chemistry reactions with alkynes. The PFP group can react with amines to form stable bonds. PFP moieties are also less susceptible to undergo hydrolysis. The hydrophilic PEG spacer increases the water solubility of the compound. Longer PEG chains enhance the water solubility properties of the chain.
Uses
Azido-PEG8-CH2COO-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG8-CH2COO-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG8-CH2CO2-PFP Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG8-CH2CO2-PFP Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32275 | 58 |
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38664 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3955 | 55 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1986 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 55017 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
View Lastest Price from Azido-PEG8-CH2CO2-PFP manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | Azido-PEG8-CH2COO-PFP
2182601-80-3
|
US $46.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-03-24 | Azido-PEG8-CH2COO-PFP
2182601-80-3
|
US $0.00 / mg | 500mg | >98.00% | 500mg | Xian confluore Biological Technology Co., Ltd. |
-
- Azido-PEG8-CH2COO-PFP
2182601-80-3
- US $46.00 / mg
- TargetMol Chemicals Inc.
-
- Azido-PEG8-CH2COO-PFP
2182601-80-3
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.