ChemicalBook >> CAS DataBase List >>JNJ 17029259
JNJ 17029259
- CAS No.
- 314267-57-7
- Chemical Name:
- JNJ 17029259
- Synonyms
- JNJ 17029259;4-[4-(2-aminopropan-2-yl)phenyl]-2-[4-(2-morpholin-4-ylethyl)anilino]pyrimidine-5-carbonitrile;5-Pyrimidinecarbonitrile, 4-[4-(1-amino-1-methylethyl)phenyl]-2-[[4-[2-(4-morpholinyl)ethyl]phenyl]amino]-
- CBNumber:
- CB32668377
- Molecular Formula:
- C26H30N6O
- Molecular Weight:
- 442.56
- MDL Number:
- MFCD25977027
- MOL File:
- 314267-57-7.mol
Last updated:2025-04-18 09:52:05
| Boiling point | 660.3±65.0 °C(Predicted) |
|---|---|
| Density | 1.24±0.1 g/cm3(Predicted) |
| pka | 8.49±0.10(Predicted) |
| FDA UNII | 95RGX89OQD |
JNJ 17029259 Chemical Properties,Uses,Production
Uses
JNJ 17029259 is an orally active and selective VEGF-R2 kinase inhibitor. JNJ 17029259 inhibits VEGF-mediated signal transduction. JNJ 17029259 has anti-angiogenic activity[1][2].
References
[1] Mohammed S. I. Makki, et al. Fluorine Substituted 1,2,4-Triazinones as Potential Anti-HIV-1 and CDK2 Inhibitors. Journal of Chemistry. 2014. Article ID 430573.
[2] Reuman M, et al. Scalable synthesis of the VEGF-R2 kinase inhibitor JNJ-17029259 using ultrasound-mediated addition of MeLi-CeCl3 to a nitrile. J Org Chem. 2008 Feb 1;73(3):1121-3. DOI:10.1021/jo7021372
JNJ 17029259 Preparation Products And Raw materials
Raw materials
Preparation Products
JNJ 17029259 Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32281 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19903 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 20614 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from JNJ 17029259 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | JNJ-17029259
314267-57-7
|
US $1820.00-3100.00 / mg | 10g | TargetMol Chemicals Inc. |
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- JNJ-17029259
314267-57-7
- US $1820.00-3100.00 / mg
- TargetMol Chemicals Inc.
JNJ 17029259
4-[4-(2-aminopropan-2-yl)phenyl]-2-[4-(2-morpholin-4-ylethyl)anilino]pyrimidine-5-carbonitrile
5-Pyrimidinecarbonitrile, 4-[4-(1-amino-1-methylethyl)phenyl]-2-[[4-[2-(4-morpholinyl)ethyl]phenyl]amino]-
314267-57-7