CBZ-aminooxy-PEG8-acid
- CAS No.
- 2353410-09-8
- Chemical Name:
- CBZ-aminooxy-PEG8-acid
- Synonyms
- CBZ-aminooxy-PEG8-acid;3,6,9,12,15,18,21,24,27-Nonaoxa-2-azatriacontanedioic acid, 1-(phenylmethyl) ester
- CBNumber:
- CB54849567
- Molecular Formula:
- C27H45NO13
- Molecular Weight:
- 591.65
- MDL Number:
- MFCD31693699
- MOL File:
- 2353410-09-8.mol
CBZ-aminooxy-PEG8-acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-24120 | CBZ-aminooxy-PEG8-acid 97% | 2353410-09-8 | 100mg | $360 | 2021-12-16 | Buy |
| BroadPharm | BP-24120 | CBZ-aminooxy-PEG8-acid 97% | 2353410-09-8 | 250mg | $680 | 2021-12-16 | Buy |
| BroadPharm | BP-24120 | CBZ-aminooxy-PEG8-acid 97% | 2353410-09-8 | 500mg | $1020 | 2021-12-16 | Buy |
CBZ-aminooxy-PEG8-acid Chemical Properties,Uses,Production
Description
CBZ-aminooxy-PEG8-acid is an aqueous soluble PEG linker containing a CBZ-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The protected aminooxy can be deprotected under acidic conditions.
Uses
Cbz-aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
CBZ-aminooxy-PEG8-acid Preparation Products And Raw materials
Raw materials
Preparation Products
CBZ-aminooxy-PEG8-acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32281 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1986 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 9994 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29772 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| Shanghai Easy CDMO Co.,Ltd | 021-61734564 13854185395; | info@easycdmo.com | China | 10030 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 27958 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 176345344 7 17634854698 | 1959525201@qq.com | China | 8069 | 58 |