Azido-PEG1-CH2CO2tBu
- CAS No.
- 1820717-35-8
- Chemical Name:
- Azido-PEG1-CH2CO2tBu
- Synonyms
- CAS_1820717-35-8;Azido-PEG1-C1-Boc;Azido-PEG1-CH2COOtBu;Azido-PEG1-CH2CO2tBu;Azido-PEG1-t-butyl acetate;Azido-PEG1-CH2COOH t-Bu Ester;Azido-PEG1-CH2CO2-t-butyl ester;tert-Butyl 2-(2-azidoethoxy)acetate;Azido-PEG1-CH2CO2-t-Bu,Azido-PEG1-CH2CO2-t-butyl Ester
- CBNumber:
- CB83162860
- Molecular Formula:
- C8H15N3O3
- Molecular Weight:
- 201.23
- MDL Number:
- MFCD27635154
- MOL File:
- 1820717-35-8.mol
Azido-PEG1-CH2CO2tBu price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A965980 | Azido-PEG1-CH2CO2-t-butylEster | 1820717-35-8 | 5mg | $45 | 2021-12-16 | Buy |
| BroadPharm | BP-22060 | Azido-PEG1-CH2CO2-t-Bu 98% | 1820717-35-8 | 250mg | $250 | 2021-12-16 | Buy |
| Acrotein | B-0921 | tert-Butyl2-(2-azidoethoxy)acetate 97% | 1820717-35-8 | 1g | $495 | 2021-12-16 | Buy |
Azido-PEG1-CH2CO2tBu Chemical Properties,Uses,Production
Description
Azido-PEG1-CH2CO2-t-Bu is a azide (N3) containing PEG linker.The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG1-CH2CO2tBu Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32281 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3951 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 | |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 10205 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28794 | 58 |