SR 1903
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- $37 - $249
- Product name: SR 1903
- CAS: 1414248-06-8
- MF: C27H27F6N3O
- MW: 523.52
- EINECS:
- MDL Number:
- Synonyms:SR 1903;[1,1'-Biphenyl]-4-methanol, 2'-methyl-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-;2'-methyl-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol;1,1,1,3,3,3-Hexafluoro-2-(2'-methyl-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)propan-2-ol;1,1,1,3,3,3-Hexafluoro-2-[4-[2-methyl-4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol
3 prices
Selected condition：
Brand
- Cayman Chemical
Package
- 1mg
- 5mg
- 10mg
- ManufacturerCayman Chemical
- Product number28253
- Product descriptionSR 1903
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28253
- Product descriptionSR 1903
- Packaging5mg
- Price$134
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28253
- Product descriptionSR 1903
- Packaging10mg
- Price$249
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 28253 | SR 1903 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 28253 | SR 1903 | 5mg | $134 | 2024-03-01 | Buy |
| Cayman Chemical | 28253 | SR 1903 | 10mg | $249 | 2024-03-01 | Buy |
Properties
Boiling point :559.0±50.0 °C(Predicted)
Density :1.307±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :9.23±0.15(Predicted)
Density :1.307±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :9.23±0.15(Predicted)
Safety Information
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Description
SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR). It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated receptor γ (PPAR) but does not activate it. SR-1903 inhibits LPS-induced expression of triggering receptor expressed on myeloid cells 1 (TREM-1). It also inhibits LPS-induced expression of the LXR target genes IL-6 and IL-33 and increases expression of ABCG1, FASN, and SCD-1. SR-1903 reduces the severity of collagen-induced arthritis. It reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity.Suppliers and manufacturers
BOC Sciences
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Nanjing Tengyi Biotechnology Co., Ltd
Shanghai Yifei Biotechnology Co. , Ltd.
TargetMol Chemicals Inc.
Changzhou Yourui Pharmaceutical Technology Co., Ltd
Cayman Chemical Company
Biosynth Biological Technology (Suzhou) Co Ltd
