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1953-04-4 Basic information More..
Product Name:Galantamine Hydrobromide
Synonyms:(-)-Galanthaminium bromide;Hydrobromic acid·galanthamine;galanthamine hydrobromide from lycoris sp.;Galanthamine Hydrobromide Injection;GALANTHAMINE HYDROBROMIDUM;Lycorisradiata(l'.aher.)herb;Galanthamine hydrobromide from Lycoris sp.,Galantamine hydrobromide;Galantamine Hydrobromide (200 mg)
CAS:1953-04-4
MF:C17H22BrNO3
MW:368.27
EINECS:217-780-5
Mol File:1953-04-4.mol
1953-04-4

Use

Galantamine hydrobromide is a kind of tertiary amino alkaloid and is a reversible competitive inhibitor of cholinesterase. With the deepened understanding of the Alzheimer’s disease (AD) pathogenesis, people have started the study of using this product for treating AD in the early 1980s. In 1987, the United States scholars Bonnie had first successfully receive a patent of applying galantamine hydrobromide for treatment of AD. After this, many countries, one after another, have carried out related pharmacological, pharmacodynamic and pharmacokinetic studies related to it. This result had showed that galantamine hydrobromide, as the second-generation cholinesterase inhibitors, targeted on nerve synapses by competing with acetylcholine for binding to the cholinesterase and further blocking this enzymatic degradation of acetylcholine and therefore increasing the acetyl choline concentration inside the brain.

Galantamine Hydrobromide manufacturers

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