Chemical Properties | Back Directory | [Boiling point ]
1060.2±65.0 °C(Predicted) | [density ]
1.074±0.06 g/cm3(Predicted) | [pka]
13.25±0.70(Predicted) | [Sequence]
Cyclo(-D-Ala-D-allo-Ile-Val-D-Leu-Leu-Trp) |
Hazard Information | Back Directory | [Uses]
Baceridin is a proteasome inhibitor and a cyclic hexapeptide. Baceridin can be isolated from the culture medium of Epiphytic Bacillus. Baceridin can inhibit cell cycle progression and induce tumor cell apoptosis through a p53-independent pathway. Baceridin can be used in cancer research[1]. | [References]
[1] Niggemann J, et al. Baceridin, a cyclic hexapeptide from an epiphytic bacillus strain, inhibits the proteasome. Chembiochem. 2014 May 5;15(7):1021-9. DOI:10.1002/cbic.201300778 |
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