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(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Suppliers list
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Products Intro: Product Name:(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
CAS:16626-02-1
Purity:98% Package:5KG;1KG
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Products Intro: Product Name:(S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid
CAS:16626-02-1
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Products Intro: Product Name:H-Trp(5-F)-OH
CAS:16626-02-1
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Products Intro: Product Name:H-Trp(5-F)-OH
CAS:16626-02-1
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Products Intro: Product Name:(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
CAS:16626-02-1
Purity:98%+ Package:100g；500g；1kg；25kg Remarks:Spot supply
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Basic information
Product Name:(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
Synonyms:5-FLUORO-L-TRYPTOPHAN;5-FLUORO-L-TRYPTOPHAN MONOHYDRATE;H-5-FLUORO-TRP-OH H2O;L-5-FLUOROTRYPTOPHAN;(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID;5-Fluoro-tryptophan monohydrate;H-L-Trp(5-F)-OH*H2O;L-5-fluorotryptophan monohydrate
CAS:16626-02-1
MF:C11H11FN2O2
MW:222.22
EINECS:
Product Categories:Indoles and derivatives;FA - FLEnzyme Inhibitors;Substrate AnalogsPeptide Synthesis;Alphabetic;Enzyme Inhibitors by Type;F;Tryptophan Derivatives;Unnatural Amino Acid Derivatives
Mol File:16626-02-1.mol
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Structure
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Chemical Properties
Melting point 238-239 °C
Boiling point 450.7±45.0 °C(Predicted)
density 1.442±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form powder
pka2.21±0.10(Predicted)
color white
BRN 5052680
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10
HS Code 2933998090
MSDS Information
ProviderLanguage
SigmaAldrich English
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Usage And Synthesis
UsesExogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since 19F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.
Biochem/physiol Actions5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.
Purification MethodsRecrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]
(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Preparation Products And Raw materials
Tag:(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID(16626-02-1) Related Product Information
Azelaic acid 5-Hydroxymethylfurfural Isoimperatorin Phosphatidylserine Soapnut Extract (-)-Huperzine A L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE 4-Aminobutyric acid Astaxanthin (2S)-2-Amino-3-(6-fluoro-1H-indol-3-yl)propionic acid,(S)-2-AMINO-3-(6-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID (S)-2-AMINO-3-(4-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID 7-CHLORO-L-TRYPTOPHAN (S)-2-AMINO-3-(4-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID (S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID H-TRP-GLY-OH (2S)-2-amino-3-(5-bromo-1H-indol-3-yl)propanoic acid 6-broMo-L-tryptophan H-TRP(BOC)-OH
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