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Doramectin monosaccharide

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CAS:165108-44-1
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CAS:165108-44-1
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CAS:165108-44-1
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CAS:165108-44-1
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CAS:165108-44-1
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Doramectin monosaccharide Basic information
Product Name:Doramectin monosaccharide
Synonyms:Doramectin monosaccharide;25-?Cyclohexyl-?4'-?O-?de(2,?6-?dideoxy-?3-?O-?methyl-?α-?L-?arabino-?hexopyranosyl)?-?5-?O-?demethyl-?25-?de(1-?methylpropyl)?-Avermectin A1a;Avermectin A1a, 25-cyclohexyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-25-de(1-methylpropyl)-
CAS:165108-44-1
MF:C43H62O11
MW:754.946
EINECS:
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Mol File:165108-44-1.mol
Doramectin monosaccharide Structure
Doramectin monosaccharide Chemical Properties
Melting point >153°C (dec.)
Boiling point 890.7±65.0 °C(Predicted)
density 1.25±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka12.42±0.70(Predicted)
color White to Off-White
Safety Information
MSDS Information
Doramectin monosaccharide Usage And Synthesis
Uses25-?Cyclohexyl-?4''-?O-?de(2,?6-?dideoxy-?3-?O-?methyl-?α-?L-?arabino-?hexopyranosyl)?-?5-?O-?demethyl-?25-?de(1-?methylpropyl)?-Avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals.
UsesDoramectin monosaccharide is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of doramectin. Doramectin monosaccharide is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. Despite the importance of doramectin as an anthelmintic in animal health, there are no published reports of the biological activity or the levels of doramectin monosaccharide in animals or in the environment.
Doramectin monosaccharide Preparation Products And Raw materials
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