| Company Name: |
Shanghai Lanle Bird Industrial Co., Ltd.
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| Tel: |
15021845385 |
| Email: |
765325601@qq.com |
| Products Intro: |
Product Name:PF-04753299;LpxC inhibitor 1a
CAS:1289620-49-0
Purity:98% Package:250mg;500mg;1g;5g;10g;100g Remarks:in stock
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:PF-04753299 >=98%
CAS:1289620-49-0
Purity:NULL Package:25mg;5mg Remarks:NULL
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LpxC inhibitor 1a manufacturers
- PF-04753299
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- $68.00 / 1mg
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2024-11-11
- CAS:1289620-49-0
- Min. Order:
- Purity: 99.63%
- Supply Ability: 10g
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| | LpxC inhibitor 1a Basic information |
| Product Name: | LpxC inhibitor 1a | | Synonyms: | LpxC inhibitor 1a;PF-04753299;[1,1'-Biphenyl]-4-butanamide, N-hydroxy-α-methyl-α-(methylsulfonyl)-, (αR)-;PF-04753299 >=98%;PF04753299,PF 04753299 | | CAS: | 1289620-49-0 | | MF: | C18H21NO4S | | MW: | 347.43 | | EINECS: | | | Product Categories: | | | Mol File: | 1289620-49-0.mol |  |
| | LpxC inhibitor 1a Chemical Properties |
| density | 1.249±0.06 g/cm3(Predicted) | | storage temp. | room temp | | solubility | DMSO: 34.7mg/mL | | form | A solid | | pka | 8.18±0.50(Predicted) | | color | White to off-white |
| | LpxC inhibitor 1a Usage And Synthesis |
| Description | PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model. | | Uses | PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine?deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection[1]. | | References | [1] Constance M John, et al. Treatment of human challenge and MDR strains of Neisseria gonorrhoeae with LpxC inhibitors. J Antimicrob Chemother. 2018 Aug 1;73(8):2064-2071. DOI:10.1093/jac/dky151 |
| | LpxC inhibitor 1a Preparation Products And Raw materials |
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