α-Hydroxyglutaric Acid Lithium NEW
| Price | $34 | $79 | $127 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-09 |
Product Details
| Product Name: α-Hydroxyglutaric Acid Lithium | Purity: ≥98% |
| Supply Ability: 10g | Release date: 2025/05/09 |
Product Introduction
Bioactivity
| Name | α-Hydroxyglutaric Acid Lithium |
| Description | α-Hydroxyglutaric Acid Lithium, converted from glutamate in microorganisms and animals, is an inhibitor of α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase, and has an inhibitory effect on ATP synthase and mTOR signaling. |
| In vitro | α-Hydroxyglutaric Acid Lithium inhibits the activity of multiple histone demethylases. In the active site of histone demethylases, α-Hydroxyglutaric Acid Lithium occupies the same space as α-KG, leading to inhibition of their activity. Additionally, α-Hydroxyglutaric Acid Lithium inhibits the activity of TET 5-methylcytosine hydroxylases[1].Treatment of U-87MG cells with α-Hydroxyglutaric Acid Lithium at concentrations ranging from 10 to 50 mM results in increased levels of HIF-1α and decreased levels of endostatin[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : < 1 mg/mL (insoluble or slightly soluble), Sonication is recommended. |
| Keywords | αHydroxyglutaricAcidLithium(2889318Freebase) | mTOR | histidine decarboxylase | EndogenousMetabolite | Endogenous Metabolite |
| Inhibitors Related | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | L-Methionine | Oleamide | Glycerol | Thymidine | Naringin | L-Ascorbic acid sodium salt | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Kinase Inhibitor Library | Hematonosis Compound Library | Autophagy Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Neuronal Differentiation Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $0.00/1kg |
VIP3Y
|
Henan Aochuang Chemical Co.,Ltd.
|
2022-09-28 | |
| $39.00/5mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2025-04-27 | |
| $50.00/1kg |
VIP3Y
|
Hebei Miaoyin Technology Co.,Ltd
|
2023-03-09 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY