2-Methylpyrimidine-5-carboxylic acid NEW
| Price | Get Latest Price |
| Package | 200kg |
| Min. Order: | 1000kg |
| Supply Ability: | 20 tons |
| Update Time: | 2025-04-02 |
Product Details
| Product Name: 2-Methylpyrimidine-5-carboxylic acid | CAS No.: 5194-32-1 |
| Min. Order: 1000kg | Purity: 0.99 |
| Supply Ability: 20 tons | Release date: 2025/04/02 |
2-Methylpyrimidine-5-carboxylic Acid CAS 5194-32-1 | Leading Supplier of High-Activity Pyrimidine Carboxylic Acid Intermediates
[Core Keywords]: 2-Methylpyrimidine-5-carboxylic Acid Supplier, CAS 5194-32-1, Pyrimidine Carboxylic Acid Pharmaceutical Intermediate, Agrochemical Fungicide Building Block
Product Basics
Chemical Name: 2-Methylpyrimidine-5-carboxylic Acid
CAS No.: 5194-32-1 (Primary Keyword Emphasis)
Molecular Formula: C?H?N?O?
Appearance: White to off-white crystalline powder
Purity: ≥98.5% (HPLC, pharmaceutical intermediate grade)
Key Physicochemical Properties (Structured Data Optimization)
| Attribute | Value |
|---|---|
| Molecular Weight | 138.12 g/mol |
| Melting Point | 245-248℃ (decomposes, DSC-tested) |
| Solubility | Freely soluble in alkaline solution (pH>10); slightly soluble in DMSO; insoluble in ethanol, acetone |
| pKa (25℃) | Carboxyl: 2.5±0.3, Pyrimidine ring: 4.8±0.2 |
| Storage Conditions | Light-protected, airtight, stored in dry at room temperature |
Integrated Industry Chain
? Upstream Material Guarantee
Core Intermediates: Methyl 2-methylpyrimidine-5-carboxylate, Sodium hydroxide
Process Optimization: Alkaline hydrolysis technology (conversion >95%, impurities <0.3%)
? Downstream Applications
Anticancer Drugs: Key precursor for thymidylate synthase inhibitors
Agrochemical Fungicides: Molecular modification of pyrimidine derivatives (e.g., pyrimethanil)
Functional Materials: Metal-organic framework (MOF) ligand synthesis
Molecular Probes: Development of nucleic acid base analogs
Industry Solutions & Technical Advantages
| Application Field | Typical Scenario | Technical Strengths |
|---|---|---|
| Anticancer Drugs | 5-Fluorouracil derivative optimization | Carboxyl-directed esterification yield >93% (LC-MS verified) |
| Agrochemicals | Resistance-management fungicide R&D | Hydrolytic stability >90% (pH 5-9) |
| Eco-Materials | Heavy metal ion chelating agents | Chelation capacity ≥2.8 mmol/g (Cu2?) |
| Diagnostics | Fluorescent probe linker synthesis | Carboxyl activation efficiency >95% |
SEO Keyword Matrix
Core Keywords:
"2-Methylpyrimidine-5-carboxylic Acid Price"
"CAS 5194-32-1 Technical Data"
"High-Purity Pyrimidine Carboxylic Acid Supplier"
Long-Tail Keywords:
"Thymidylate Synthase Inhibitor Intermediate Manufacturer"
"Pyrimethanil API Synthesis Supplier"
"Pharmaceutical-Grade CAS 5194-32-1 Producer"
Compliance Statements
? EINECS Status: Not listed (per ECHA database)
? REACH Progress: Under consortium registration (SIEF member ID: CHEM-2023-XXXXX)
? EU Export: Supports tonnage-level formal registration (SVHC test reports available)
? Analysis Reports: Full documentation provided (HPLC, 13C NMR, FTIR)
Company Profile Introduction
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China- Since: 2004-04-13
- Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China