3,?5,?6,?7,?8,?3',?4'-?Heptemthoxyflavone NEW
| Price | $89 | $222 | $328 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-09 |
Product Details
| Product Name: 3,?5,?6,?7,?8,?3',?4'-?Heptemthoxyflavone | CAS No.: 1178-24-1 |
| Purity: 99.69% | Supply Ability: 10g |
| Release date: 2025/05/09 |
Product Introduction
Bioactivity
| Name | 3,?5,?6,?7,?8,?3',?4'-?Heptemthoxyflavone |
| Description | 3,5,6,7,8,3',4'-Heptemthoxyflavone exhibits neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging, and photoprotective effects; it inhibits collagenase activity, induces type I procollagen synthesis in HDFn cells, and combats nitric oxide (NO) carcinogenesis. |
| In vitro | 3,5,6,7,8,3',4'-Heptamethoxyflavone (HMF), extracted from C. unshiu peels using ethanol extraction and hexane fractionation, inhibited collagenase activity and increased type I procollagen content in UV-induced human dermal fibroblast neonatal (HDFn) cells. HMF also suppressed matrix metalloproteinases 1 (MMP-1) expression and induced type I procollagen protein expression in these cells. Additionally, HMF inhibited UVB-induced phosphorylation of MAPK cascade signaling components—ERK, JNK, and c-Jun—thereby reducing MMP-1 expression. Furthermore, HMF modulated the TGF-β/Smad signaling pathway by inducing Smad3 and suppressing Smad7 protein expressions in a dose-dependent manner in UV-induced HDFn cells. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 12 mg/mL (27.75 mM), Sonication is recommended. |
| Keywords | TNF-α | Inhibitor | inhibit | IL Receptor | gp120/CD4 | 3,5,6,7,8,3',4'-Heptemthoxyflavone | 3,?5,?6,?7,?8,?3',?4'-?Heptemthoxyflavone | 3,?5,?6,?7,?8,?3',?4'?Heptemthoxyflavone | 3,?5,?6,?7,?8,?3',?4' ?Heptemthoxyflavone |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Flavonoid Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Miao medicine Compound Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Neuroprotective Compound Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Food as Medicine Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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$78.00 / 1mg
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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