5-HT2B antagonist-1 NEW
| Price | $38 | $58 | $119 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-09 |
Product Details
| Product Name: 5-HT2B antagonist-1 | CAS No.: 393129-91-4 |
| Purity: 99.88% | Supply Ability: 10g |
| Release date: 2025/05/09 |
Product Introduction
Bioactivity
| Name | 5-HT2B antagonist-1 |
| Description | 5-HT2B antagonist-1 is an orally active 5-HT2B receptor antagonist with an IC50 of 33.4 nM, suitable for studies of diseases characterized by 5-HT2B receptor signaling, such as hepatocellular carcinoma, cardiovascular disease, or gastrointestinal disease [1] [2]. |
| In vitro | 5-HT2B antagonist-1 (compound 5g) exhibits sodium channel binding activity with IC50 values ranging from 12.6 to 57.5 μM [1] and inhibits 5-HT2B receptor activity by less than 50% at 1 μM in CHO-K1 cell lines (compound 1-e) [3]. |
| In vivo | The oral administration of 5-HT2B antagonist-1 (compound 15) at a dosage of 30 mg/kg significantly reduces visceral hypersensitivity in irritable bowel syndrome (IBS) rats [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | WAY388264A | 5-HT2B antagonist-1 | WAY 388264 A |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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