Description of 6-(Ferrocenyl)hexanethiol from Wuhan Fortuna Chemical Co.,Ltd

Specifications(COA) of 6-(Ferrocenyl)hexanethiol CAS 134029-92-8

Introduction of 6-(Ferrocenyl)hexanethiol is an organometallic molecule comprising a six-carbon chain (hexanethiol) with a thiol (-SH) group at one end and a ferrocene group (iron sandwiched between two cyclopentadienyl rings) at the other. The thiol enables strong binding to metal surfaces (e.g., gold), forming self-assembled monolayers (SAMs), while the redox-active ferrocene provides electrochemical functionality. Widely used in biosensors, molecular electronics, and surface chemistry, it facilitates electron transfer in devices or acts as a mediator in electrochemical detection. Synthesis typically involves coupling ferrocene derivatives to protected thiol-terminated hexane chains. Requires careful handling due to thiol toxicity and air sensitivity. Combines organic/inorganic properties for versatile applications.

Application of 6-(Ferrocenyl)hexanethiol is an organometallic compound with the following structure and characteristics:

Structure

Hexanethiol Backbone: A six-carbon (hexane) chain with a thiol (-SH) group at one end (carbon 1).

Ferrocenyl Group: A ferrocene moiety (Fc), consisting of an iron atom sandwiched between two cyclopentadienyl rings, attached to the sixth carbon of the hexane chain. This creates a linear structure: HS-(CH?)?-Fc.

Key Features

1.     Redox Activity: The ferrocene group undergoes reversible oxidation/reduction (Fe2? ? Fe3?), making the compound useful in electrochemical applications.

2.     Self-Assembly: The thiol group binds strongly to gold and other noble metals, enabling the formation of self-assembled monolayers (SAMs) on surfaces.

Applications

Electrochemical Sensors: Leverages ferrocene's redox properties for detecting biomolecules or analytes.

Molecular Electronics: SAMs of this compound can act as conductive or insulating layers in nanoscale devices.

Surface Chemistry: Used to modify electrode surfaces for studying electron-transfer processes.

Synthesis

Typically involves attaching a ferrocene derivative to a hexane chain terminating in a protected thiol (e.g., via bromohexane intermediates or coupling reactions). The thiol group is often protected (e.g., as a disulfide) during synthesis to prevent oxidation.

Safety Considerations

Thiol Handling: Requires a fume hood due to potential odor and toxicity.

Ferrocene Stability: Generally stable but should be handled with standard organometallic precautions (gloves, eye protection).

Example Use Case

In biosensors, 6-(Ferrocenyl)hexanethiol can immobilize biomolecules (e.g., enzymes) on a gold electrode. The ferrocene acts as an electron mediator, enhancing signal transduction during redox reactions.

This compound bridges organic and inorganic chemistry, offering versatile functionality in both research and industrial settings.

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is  the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.

Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide 6-(Ferrocenyl)hexanethiol with good quality and best price, welcome to contact us to get COA/TDS/MSDS of 6-(Ferrocenyl)hexanethiol.