ATPγS tetralithium salt NEW
| Price | $70 | $169 | $293 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-03 |
Product Details
| Product Name: ATPγS tetralithium salt | CAS No.: 93839-89-5 |
| Purity: 90% | Supply Ability: 10g |
| Release date: 2025/06/03 |
Product Introduction
Bioactivity
| Name | ATPγS tetralithium salt |
| Description | ATPγS tetralithium salt is a good substrate for RNA-stimulated nucleotide hydrolysis and RNA unwinding activity of eIF4A. |
| In vitro | ATPγS tetralithium salt enhances intrinsic fluorescence and induces aggregation, thereby increasing spinach Rubisco activating enzyme activity. The concentration dependence of the ATPγS tetralithium salt effect is S-shaped, but at pH 8, the half-saturation requirement of ATPγS tetralithium salt (12 μM) is consistent with that measured indirectly using the fluorescent probe 1-anilinolyl-8-sulfonate. The binding affinities (6 μM) are not much different. [2] |
| In vivo | METHODS: A mouse model of ALI induced by intratracheal administration of endotoxin/lipopolysaccharide (LPS) and cultured lung ECs was used and treated with ATPγS tetralithium salt (50-100 μM final blood concentration). RESULTS ATPγS tetralithium salt attenuated the inflammatory response, reduced the accumulation of cells (48%, P < 0.01) and proteins (57%, P < 0.01) in bronchoalveolar lavage fluid, and reduced neutrophil infiltration and Evans blue albumin dye extravasation into lung tissue. [3] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 100 mg/mL (182.82 mM), Sonication is recommended. |
| Keywords | eIF4E-Eif4g | ATPγS tetralithium | ATPγS | ATPrS tetralithium | ATPrS | ATP-gamma-S tetralithium | ATPgammaS tetralithium | ATP-gamma-S | ATPgammaS |
| Inhibitors Related | MSU-42011 | BTdCPU | GP 1a | GSK2606414 | GCN2-IN-7 | DNL343 | ISRIB (trans-isomer) | Azoramide | SHP099 | PERK-IN-4 | CCT020312 | 4EGI-1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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