CDDO-dhTFEA NEW

Price	$64	$93	$155
Package	1mg	2mg	5mg

Min. Order:
Supply Ability:	10g
Update Time:	2025-06-12

Product Details

Product Name: CDDO-dhTFEA	CAS No.: 1191265-33-4
Purity: 99.59%	Supply Ability: 10g
Release date: 2025/06/12

Product Introduction

Bioactivity

Name	CDDO-dhTFEA
Description	CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expression of related genes, attenuates NF-κB and transforming growth factor-β pathway activation, and mitigates glomerulosclerosis, interstitial fibrosis, and inflammation in rats with chronic kidney disease (CKD).
In vivo	CDDO-dhTFEA restores hypertension, increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis, and inflammation in the chronic kidney disease rats [2].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 100 mg/mL (174.00 mM), Sonication is recommended.
Keywords	RTA dh-404 \| RTA dh404 \| RTA dh 404 \| Nuclear factor-κB \| Nuclear factor-kappaB \| Nrf2 \| NF-κB \| NFκB \| NF-kB \| NFkB \| Keap1-Nrf2 \| Inhibitor \| inhibit \| CDDO-dhTFEA \| CDDOdhTFEA \| CDDO dhTFEA
Inhibitors Related	TBHQ \| Dimethyl fumarate \| Lidocaine \| Diethylmaleate \| Resveratrol \| Curcumin \| Glucosamine \| sodium lauroyl-α-hydroxyethyl sulfonate \| Lidocaine hydrochloride \| 5-Aminosalicylic Acid \| Indole-3-carbinol \| Diallyl disulfide
Related Compound Libraries	Anti-Lung Cancer Compound Library \| Ferroptosis Compound Library \| Anti-Pancreatic Cancer Compound Library \| Bioactive Compound Library \| Antioxidant Compound Library \| Inhibitor Library \| Immunology/Inflammation Compound Library \| Anti-Aging Compound Library \| Bioactive Compounds Library Max \| Fluorochemical Library \| Anti-Cancer Active Compound Library \| Transcription Factor-Targeted Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.