
Kif15-IN-1 NEW
Price | $499 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-04-28 |
Product Details
Product Name: Kif15-IN-1 | CAS No.: 672926-32-8 |
Purity: 99.39% | Supply Ability: 10g |
Release date: 2025/04/28 |
Product Introduction
Bioactivity
Name | Kif15-IN-1 |
Description | Kif15-IN-1 is a kinesin family 15 (Kif15) inhibitor with antiproliferative activity and potential anticancer activity, which can be used to study gastric cancer. |
In vitro | Concentration response analysis using the MT gliding assay revealed that the IC50 was 203 nM, significantly lower than the previous study. Concentration response curve using the MT-gliding assay, developed from 5 concentrations of Kif15-IN-1, ranging from 30 to 0.1 μM. Kif15-IN-1 is a competitive ATP inhibitor. Double reciprocal Lineweaver-Burk plot of ATP titration using 5 μM Kif15-IN-1. An increase in KMATP was observed when the ATP concentration was varied in the presence of Kif15-IN-1, indicating that Kif15-IN-1 competes with ATP binding. [1] |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O : < 0.1 mg/mL (insoluble) DMSO : 80 mg/mL (185.84 mM), Sonication is recommended. |
Keywords | Kif15-IN-1 | Kif-15-IN-1 | Kif15IN1 | Kif15 IN 1 | Kif15 | KIF15 |
Inhibitors Related | Eg5-IN-1 | Eg5 Inhibitor V, trans-24 | AZD-4877 | UMK57 | BAY1217389 | BRD9876 | Paprotrain | SB-743921 hydrochloride | S-trityl-L-Cysteine | Empesertib | MPI-0479605 | CW-069 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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