Muramyl dipeptide NEW
| Price | $188 | $293 | $573 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Muramyl dipeptide | CAS No.: 53678-77-6 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Muramyl dipeptide |
| Description | Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. It indirectly decreases osteoclast differentiation by reducing the RANKL/OPG ratio and directly increases osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways, thereby inducing bone formation via Runx2. |
| In vitro | Muramyl dipeptide increases the protein expression of Runx2 in a dose-dependent manner (0.1-10 μg/mL; 24 hours)[1]. It also enhances the mRNA levels of Runx2 in a dose-dependent manner (0.1-10 μg/mL; 6 hours)[2]. Muramyl dipeptide indirectly attenuates osteoclast differentiation by reducing the RANKL/OPG ratio[2]. |
| In vivo | Muramyl dipeptide can be used for animal modeling to establish sepsis models. Muramyl dipeptide (1.25 mg/kg; intraperitoneal injection; twice) alleviates osteoporosis-induced bone loss[2]. |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (101.53 mM), Sonication is recommended. H2O : 20 mg/mL (40.61 mM), Sonication is recommended. |
| Keywords | NOD2 | NLRP1 | Muramyl dipeptide |
| Inhibitors Related | Dapansutrile | NOD-IN-1 | CY-09 | MCC950 sodium | Imperatorin | NLRP3-IN-10 | NLRP3-IN-2 | Bergenin | Nigericin sodium salt | NLRP3-IN-9 | INF39 | Selnoflast |
| Related Compound Libraries | NF-κB Signaling Compound Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Anti-Ovarian Cancer Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Anti-Cancer Compound Library | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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