Ozagrel hydrochloride NEW
| Price | $44 | $71 | $107 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: Ozagrel hydrochloride | CAS No.: 78712-43-3 |
| Purity: 99.80% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | Ozagrel hydrochloride |
| Description | Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. |
| In vitro | Administration of 3 mg/kg Ozagrel significantly reduces the area and volume of cortical infarcts in rats following cerebral middle artery occlusion and reperfusion. Ozagrel also inhibits neural deficits in a rat model of microthrombosis and enhances deteriorated spontaneous motor activity and motor coordination in a conscious mouse model of cerebral ischemia-reperfusion. Furthermore, Ozagrel prevents the increase in lactate dehydrogenase activity in guinea pig pulmonary lavage fluid and blocks the production of thromboxane A(2) induced by oleic acid in guinea pigs, subsequently reducing the total protein concentration and the numbers of macrophages and neutrophils, as well as the expression of monocyte chemoattractant protein-1 and interleukin-8 mRNA in the entire lung. In cats, Ozagrel inhibits the reduction of brain tissue-specific gravity induced by reperfusion in the SHR model of cerebral ischemia-reperfusion and restores the decreased cortical PO(2) post-ischemia upon reperfusion. Ozagrel also increases the level of 6-keto-PGF(1alpha), a metabolite of prostacyclin I(2) (PGI(2)), in the brain tissue following ischemia-reperfusion. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 65 mg/mL (245.55 mM), Sonication is recommended. H2O : 48 mg/mL (181.33 mM), Sonication is recommended. Ethanol : 6 mg/mL (22.67 mM), Sonication is recommended. |
| Keywords | TXA2 | Thromboxane A2 synthetase | thromboxane A2 | ProstaglandinReceptor | Prostaglandin Receptor | platelet | Ozagrel hydrochloride | Ozagrel Hydrochloride | Ozagrel | OKY-046 | OKY046 | OKY 046 | Inhibitor | inhibit | antiplatelet | aggregation |
| Inhibitors Related | Dabigatran Etexilate Mesylate | Angoroside C | (S)-(+)-Ibuprofen | Pranoprofen | Tranilast | AEBSF hydrochloride | Heparin sodium salt | Rutin | Menadione | Ozagrel | Ethamsylate | Eltrombopag Olamine |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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