PRODUCT INFORMATION

Names

Name	N-(octadecanoyl)ethanolamine
Synonym	More Synonyms

 Stearoylethanolamide Biological Activity

Description	Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity.
Related Catalog	Research Areas >> Neurological Disease Natural Products >> Others
Target	Human Endogenous Metabolite
In Vitro	Stearoylethanolamide (SEA) is present in human, rat and mouse brain in amounts comparable with those of the endocannabinoid anandamide (arachidonoylethanolamide; AEA). Stearoylethanolamide is an endocannabinoid-like compound with pro-apoptotic activity, which is regulated by NO in a way opposite to that reported for AEA[1].
References	[1]. Maccarrone M, et al. Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. Biochem J. 2002 Aug 15;366(Pt 1):137-44.

 Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	486.0±28.0 °C at 760 mmHg
Molecular Formula	C20H41NO2
Molecular Weight	327.545
Flash Point	247.7±24.0 °C
Exact Mass	327.313721
PSA	49.33000
LogP	6.88
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.464

Safety Information

Safety Phrases	22-24/25
WGK Germany	2
HS Code	2924199090

 Synthetic Route

Previous 1/3 Next

2-Aminoethanol CAS#:141-43-5 stearic acid CAS#:57-11-4 ~92% Stearoylethanolamide CAS#:111-57-9

Literature: Ottria, Roberta; Casati, Silvana; Ciuffreda, Pierangela Chemistry and Physics of Lipids, 2012 , vol. 165, # 7 p. 705 - 711

Octadecanoic ac... CAS#:111-63-7 2-Aminoethanol CAS#:141-43-5 ~93% Stearoylethanolamide CAS#:111-57-9

Literature: Iowa State University Research Foundation, Inc.; Wang, Tong; Wang, Xiaosan Patent: US2013/303795 A1, 2013 ; Location in patent: Paragraph 0069-0074;0076-0082; 0096; 0098 ;

2-Aminoethanol CAS#:141-43-5 2-Aminoethanol Stearoyl chloride CAS#:112-76-5 ~94% Stearoylethanolamide CAS#:111-57-9

Literature: Morales-Serna, Jose Antonio; Boutureira, Omar; Diaz, Yolanda; Matheu, M. Isabel; Castillon, Sergio Organic and Biomolecular Chemistry, 2008 , vol. 6, # 3 p. 443 - 446

 Precursor & DownStream

Precursor  7	Previous 1/2 Next
CAS#:141-43-5 2-Aminoethanol  CAS#:57-11-4 stearic acid  CAS#:111-63-7 Octadecanoic ac...  CAS#:112-76-5 Stearoyl chloride
DownStream  9	Previous 1/3 Next
CAS#:7596-88-5 2-(dodecanoylam...  CAS#:14246-55-0 Myristoyl-Gly-OH Myristoyl-Gly-OH CAS:14246-55-0  CAS#:2441-41-0 PALGLY  CAS#:6333-54-6 Glycine,N-(1-ox...

 Customs

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Company Profile

Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.

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