Tafenoquine NEW
| Price | $56 | $91 | $193 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-25 |
Product Details
| Product Name: Tafenoquine | CAS No.: 106635-80-7 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2025/06/25 |
Product Introduction
Bioactivity
| Name | Tafenoquine |
| Description | Tafenoquine (WR 238605) is an antimalarial prophylactic agent with schizonticidal activity, useful in hemolytic anemia research. |
| In vitro | Methods: Tafenoquine (WR 238605) was treated with macrophage cell line RAW 264.7, and the in vitro toxicity was evaluated using the MTT assay after 24 hours. Results: The IC50 value of Tafenoquine against macrophage cell line RAW 264.7 was 5.9μg/mL.[1] |
| In vivo | Methods: Tafenoquine (WR 238605) (3/6mg/kg, oral) was administered to normal C57BL/6 mice (WT) and humanized/CYP 2D6 knock-in mice, and the antimalarial activity of TQ against P. berghei expressing enzymes was evaluated by monitoring luminescence using an in vivo imaging system. Results: Tafenoquine at a dose of 3mg/kg showed no antimalarial activity in CYP 2D knock-out mice; when tested at 6mg/kg, the antimalarial activity of TQ in humanized/CYP 2D6 knock-in mice was partially restored.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | WR-238605 | Tafenoquine | Anti-malarial |
| Inhibitors Related | Picaridin | Kaempferol | Kojic acid | Urethane | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Diethyltoluamide | Artemisinin | DL-Methionine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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