98% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

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GSK 126

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2140

CAS [1346574-57-9]

MF C31H38N6O2
MW 526.67

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in DMSO

GSK 126

Description

Potent, selective, cell-active inhibitor of histone lysine methyltransferase (HMTase or HMT; H3K27 selective) EZH2 (Ki 0.57 nM; IC50 9.9 nM); more than 150-fold selective for EZH2 versus EZH1 (Ki 89 nM) and 20 other human methyltransferases. GSK126 effectively inhibits proliferation of EZH2 mutant DLBCL cell lines and growth of EZH2 mutant DLBCL xenografts in mice.
Order
Size Unit Price Stock
2 mg €75.00 In Stock
5 mg €110.00 In Stock
25 mg €380.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €560.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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