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  2. GPCR/G Protein
  3. Mas-related G-protein-coupled Receptor (MRGPR)
  4. PAMP-12(human, porcine)

PAMP-12(human, porcine) 是免疫反應性 (ir)-PAMP 的一種主要成分，由腎上腺髓質(zhì)素前體加工而成，是一種有效的降壓肽，可參與心血管方面的調(diào)控。

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Custom Peptide Synthesis

PAMP-12(human, porcine) Chemical Structure

PAMP-12(human, porcine) Chemical Structure

CAS No. : 196305-05-2

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥1200
In-stock
5 mg ￥3600
In-stock
10 mg ￥5580
In-stock
50 mg   詢價  
100 mg   詢價  

* Please select Quantity before adding items.

Customer Review

Other Forms of PAMP-12(human, porcine):

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control[1].

體外研究
(In Vitro)

PAMP-12(human, porcine) 是 C 端具有酰胺結(jié)構(gòu)的 PAMP[9-20]。給麻醉大鼠靜脈注射PAMP-12，可顯示出顯著的降血壓作用，且呈劑量依賴性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1618.93

Formula

C77H119N25O14
CAS 號
性狀

固體

顏色

White to off-white

Sequence Shortening

FRKKWNKWALSR-NH2
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
細胞實驗： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
純度 & 產(chǎn)品資料

純度: 97.27%

參考文獻

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

產(chǎn)品名稱：
PAMP-12(human, porcine)
目錄號：
HY-P2198
需求量：