Cas No.: | 29741-10-4 |
SMILES: | O=C1C2=C(C=C(C=C2OC(C3=CC(O)=C(O)C=C3)=C1)O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)O |
Formula: | C21H18O12 |
M.Wt: | 462.36 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively. |
Target: | MMP-1:17.63 μM (IC50) MMP-3:7.99 μM (IC50) MMP-8:11.42 μM (IC50) MMP-9:12.85 μM (IC50) MMP13:0.03 μM (IC50) |
References: | [1]. Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911. |